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The collecting duct system of the kidney consists of a series of tubules and ducts that physically connect nephrons to a minor calyx or directly to the renal pelvis.The collecting duct participates in electrolyte and fluid balance through reabsorption and excretion, processes regulated by the hormones aldosterone and vasopressin (antidiuretic hormone).
The collecting duct system begins in the renal cortex and extends deep into the medulla. As the urine travels down the collecting duct system, it passes by the medullary interstitium which has a high sodium concentration as a result of the loop of Henle's countercurrent multiplier system. [1]: 67
The presence of aquaporin-1 channels in the thin segment facilitates high water permeability, crucial for water reabsorption as part of the kidney's countercurrent exchange mechanism. [ 4 ] [ 5 ] They can be distinguished from the vasa recta by the absence of blood, and they can be distinguished from the thick ascending limb by the thickness of ...
A simple means of estimating renal function is to measure pH, blood urea nitrogen, creatinine, and basic electrolytes (including sodium, potassium, chloride, and bicarbonate). As the kidney is the most important organ in controlling these values, any derangement in these values could suggest renal impairment.
The juxtaglomerular apparatus is part of the kidney nephron, next to the glomerulus. It is found between afferent arteriole and the thick ascending limb of the loop of Henle (distal straight tubule) of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate. [2] [3]
The formation of urine begins within the functional unit of the kidney, the nephrons. Urine then flows through the nephrons, through a system of converging tubules called collecting ducts. These collecting ducts then join together to form the minor calyces, followed by the major calyces that ultimately join the renal pelvis. From here, urine ...
The renal corpuscle is a blood-filtering part of the nephron and is located in the cortex. The renal tubule extends from the renal corpuscle to the medulla into the loop of Henle and then returns back to the cortex. Finally, the renal tubule flows with its distal end into its collecting duct, which is common to several nephrons.
The renal calyces (sg. calyx) are conduits in the kidney through which urine passes. The minor calyces form a cup-shaped drain around the apex of the renal pyramids.Urine formed in the kidney passes through a renal papilla at the apex into the minor calyx; four or five minor calyces converge to form a major calyx through which urine passes into the renal pelvis (which in turn drains urine out ...