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  2. Outline of clinical research - Wikipedia

    en.wikipedia.org/wiki/Outline_of_clinical_research

    Academic clinical trials – clinical trials run at academic centers (e.g., medical schools, academic hospitals, and universities) Clinical trials unit – biomedical research units dedicated to conducting clinical trials; Epidemiology – the study of factors affecting the health and illness of populations

  3. Clinical study design - Wikipedia

    en.wikipedia.org/wiki/Clinical_study_design

    Randomized controlled trial [5]. Blind trial [6]; Non-blind trial [7]; Adaptive clinical trial [8]. Platform Trials; Nonrandomized trial (quasi-experiment) [9]. Interrupted time series design [10] (measures on a sample or a series of samples from the same population are obtained several times before and after a manipulated event or a naturally occurring event) - considered a type of quasi ...

  4. Case report form - Wikipedia

    en.wikipedia.org/wiki/Case_report_form

    The sponsor of the clinical trial develops the CRF to collect the specific data they need in order to test their hypotheses or answer their research questions. The size of a CRF can range from a handwritten one-time 'snapshot' of a patient's physical condition to hundreds of pages of electronically captured data obtained over a period of weeks ...

  5. Phases of clinical research - Wikipedia

    en.wikipedia.org/wiki/Phases_of_clinical_research

    Clinical trials testing potential medical products are commonly classified into four phases. The drug development process will normally proceed through all four phases over many years. [ 1 ] When expressed specifically, a clinical trial phase is capitalized both in name and Roman numeral , such as "Phase I" clinical trial.

  6. Glossary of clinical research - Wikipedia

    en.wikipedia.org/wiki/Glossary_of_clinical_research

    A clinical trial is a research study to answer specific questions about vaccines or new therapies or new ways of using known treatments. Clinical trials (also called medical research and research studies) are used to determine whether new drugs or treatments are both safe and effective.

  7. Clinical research - Wikipedia

    en.wikipedia.org/wiki/Clinical_research

    Clinical research is different from clinical practice: in clinical practice, established treatments are used to improve the condition of a person, while in clinical research, evidence is collected under rigorous study conditions on groups of people to determine the efficacy and safety of a treatment.

  8. Source document - Wikipedia

    en.wikipedia.org/wiki/Source_document

    A source document is a document in which data collected for a clinical trial is first recorded. This data is usually later entered in the case report form.The International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use (ICH-GCP) guidelines define source documents as "original documents, data, and records."

  9. Clinical epidemiology - Wikipedia

    en.wikipedia.org/wiki/Clinical_epidemiology

    Clinical epidemiology is a subfield of epidemiology specifically focused on issues relevant to clinical medicine. The term was first introduced by virologist John R. Paul in his presidential address to the American Society for Clinical Investigation in 1938. [1] [2] It is sometimes referred to as "the basic science of clinical medicine". [3]