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Treponema pallidum is a helically shaped bacterium with high motility consisting of an outer membrane, peptidoglycan layer, inner membrane, protoplasmic cylinder, and periplasmic space. [9] It is often described as gram-negative, but its outer membrane lacks lipopolysaccharide, which is found in the outer membrane of other gram-negative ...
Treponema pallidum subspecies pallidum is a spiral-shaped, Gram-negative, highly mobile bacterium. [11] [22] Two other human diseases are caused by related Treponema pallidum subspecies, yaws (subspecies pertenue) and bejel (subspecies endemicum), and one further caused by the very closely related Treponema carateum, pinta.
Treponema is a genus of spiral-shaped bacteria. The major treponeme species of human pathogens is Treponema pallidum, whose subspecies are responsible for diseases such as syphilis, bejel, and yaws. Treponema carateum is the cause of pinta. [2] Treponema paraluiscuniculi is associated with syphilis in rabbits. [3]
Syphilis is caused by the bacteria Treponema pallidum, ... a truly effective treatment wasn’t found until penicillin was first used against the bacteria in 1940, according to the study.
A breakthrough example (2020) from early modern Europe can be found in the work of Karen Giffin and her co-authors, who sequenced a genome of Treponema pallidum subspecies pertenue, the causal agent of yaws, from a Lithuanian tooth radiocarbon-dated to 1447–1616 (95 percent probability). The ability to sequence the entire genome is especially ...
Yaws is a tropical infection of the skin, bones, and joints caused by the spirochete bacterium Treponema pallidum pertenue. [6] [7] The disease begins with a round, hard swelling of the skin, 2 to 5 cm (0.79 to 1.97 in) in diameter. [6]
Thin spirochete Treponema pallidum bacteria, the causative agent of syphilis magnified 400 times. A spirochete (plural spirochetes) is a very thin, elongate, flexible, spiral bacteria that is motile via internal periplasmic flagella inside the outer membrane. [33] They comprise the phylum Spirochaetes.
Treponema pallidum subspecies which cause treponematoses such as syphilis and yaws. Brachyspira pilosicoli and Brachyspira aalborgi, which cause intestinal spirochaetosis [16] Salvarsan, the first partially organic synthetic antimicrobial drug in medical history, was effective against spirochaetes and primarily used to cure syphilis.