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Overview of the citric acid cycle. The citric acid cycle—also known as the Krebs cycle, Szent–Györgyi–Krebs cycle, or TCA cycle (tricarboxylic acid cycle) [1] [2] —is a series of biochemical reactions to release the energy stored in nutrients through the oxidation of acetyl-CoA derived from carbohydrates, fats, proteins, and alcohol.
This cycle was the first metabolic cycle to be discovered by Hans Krebs and Kurt Henseleit in 1932, [2] [3] [4] five years before the discovery of the TCA cycle. The urea cycle was described in more detail later on by Ratner and Cohen. The urea cycle takes place primarily in the liver and, to a lesser extent, in the kidneys.
2271 14194 Ensembl ENSG00000091483 ENSMUSG00000026526 UniProt P07954 P97807 RefSeq (mRNA) NM_000143 NM_010209 RefSeq (protein) NP_000134 NP_034339 Location (UCSC) Chr 1: 241.5 – 241.52 Mb Chr 1: 175.43 – 175.45 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Fumarase Identifiers EC no. 4.2.1.2 CAS no. 9032-88-6 Databases IntEnz IntEnz view BRENDA BRENDA entry ExPASy NiceZyme view ...
Significant sources of propionyl-CoA are the essential amino acids: valine, methionine, isoleucine, threonine; odd-chained fatty acids and propionic acid from intestinal bacteria. [2] When odd-chain fatty acids are oxidized, one molecule of succinyl-CoA is formed per fatty acid. The final enzyme is methylmalonyl-CoA mutase.
Fumaric acid or trans-butenedioic acid is an organic compound with the formula HO 2 CCH=CHCO 2 H. A white solid, fumaric acid occurs widely in nature. It has a fruit-like taste and has been used as a food additive.
The Reductive/Reverse TCA Cycle (rTCA cycle). Shown are all of the reactants, intermediates and products for this cycle. The reverse Krebs cycle (also known as the reverse tricarboxylic acid cycle, the reverse TCA cycle, or the reverse citric acid cycle, or the reductive tricarboxylic acid cycle, or the reductive TCA cycle) is a sequence of chemical reactions that are used by some bacteria and ...
Bubur ayam (Indonesian and Malay for "chicken congee") is a chicken congee dish served in Southeast Asia. It is rice congee with shredded chicken meat served with some condiments, such as chopped scallion, crispy fried shallot, celery, tongcay or chai poh (preserved vegetables), fried soybean, crullers (youtiao, known as cakwe in Indonesia and cakoi in Malaysia), both salty and sweet soy sauce ...
The formation of a peptide bond requires an input of energy. The two reacting molecules are the alpha amino group of one amino acid and the alpha carboxyl group of the other amino acids. A by-product of this bond formation is the release of water (the amino group donates a proton while the carboxyl group donates a hydroxyl). [2]