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Coenzyme Q10, or CoQ10, has risen in popularity. ... those using statins to decrease cholesterol, and older adults are the three main groups that may need to take CoQ10 supplements, says Winnifred ...
When examining the cost-effectiveness of statin use in older adults, the researchers report that statins were cost-effective, with the cost per quality-adjusted life years gained below £3,502 ...
A 2017 meta-analysis of people with heart failure taking 30–100 mg/d of CoQ 10 found a 31% lower mortality and increased exercise capacity, with no significant difference in the endpoints of left heart ejection fraction. [39] A 2021 meta-analysis found that coenzyme Q10 was associated with a 31% lower all-cause mortality in HF patients. [40]
The International Coenzyme Q10 Association is a nonprofit association originally based in Ancona, Italy and currently in Seville, Spain.Since its establishment in 1997, it has promoted biochemical and clinical research on the substance Coenzyme Q10 in an attempt to increase the body of knowledge about the preventive and therapeutic health effects of Coenzyme Q10.
The risk of statin-induced rhabdomyolysis increases with older age, use of interacting medications such as fibrates, and hypothyroidism. [95] [96] Coenzyme Q10 (ubiquinone) levels are decreased in statin use; [97] CoQ10 supplements are sometimes used to treat statin-associated myopathy, though evidence of their efficacy is lacking as of 2017. [98]
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