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Work done 12 years later found that the serum phenobarbital 0.111 mg/100 mL for every mg/kg of primidone ingested. Authors publishing a year earlier estimated that 24.5% of primidone was metabolized to phenobarbital, but the patient reported by Kappy and Buckley would have had a serum level of 44.4 mg/100 mL instead of 8.5 mg/100 mL if this ...
Chemical structure of the prototypical NaSSA mirtazapine (original brand name Remeron). Noradrenergic and specific serotonergic antidepressants (NaSSAs) are a class of psychiatric drugs used primarily as antidepressants. [1]
Concerta (methylphenidate) – an extended release form of methylphenidate Contrave ( naltrexone/bupropion ) – a combination drug used in the treatment of mood and psychotic disorders. It is also approved for weight loss in those that are either obese or overweight with some weight-related illnesses
A prodrug is a pharmacologically inactive medication or compound that, after intake, is metabolized (i.e., converted within the body) into a pharmacologically active drug. [1] [2] Instead of administering a drug directly, a corresponding prodrug can be used to improve how the drug is absorbed, distributed, metabolized, and excreted ().
Multiple convenience and random samples, as well as research studies in both clinical and nonclinical sample [22] [1] [23] Internal consistency (Cronbach's alpha, split half, etc.) Good Cronbach's alpha reported at .88 for measuring depression [22] Inter-rater reliability: Good Kappas range from .64-.81 for depression. [24] Kappa for anxiety is ...
"Depression" refers to a spectrum of disturbances in mood that vary from mild to severe and from short periods to constant illness. [1] DD-NOS is diagnosed if a patient's symptoms fail to meet the criteria more common depressive disorders such as major depressive disorder or dysthymia .
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