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  2. List of polysubstance combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_polysubstance...

    The prescription medicine Adderall (dextroamphetamine sulfate/amphetamine sulfate/dextroamphetamine saccharate/amphetamine aspartate monohydrate) is also frequently used recreationally. However, using non-prescribed drugs, using non-prescribed dose regimen, can cause polysubstance dependence , or combined drug intoxication which may lead to ...

  3. Caffeine - Wikipedia

    en.wikipedia.org/wiki/Caffeine

    When alcohol and caffeine are consumed jointly, the effects of the caffeine are changed, but the alcohol effects remain the same. [157] For example, consuming additional caffeine does not reduce the effect of alcohol. [157] However, the jitteriness and alertness given by caffeine is decreased when additional alcohol is consumed. [157]

  4. Effect of psychoactive drugs on animals - Wikipedia

    en.wikipedia.org/wiki/Effect_of_psychoactive...

    Psychoactive drugs, such as alcohol, caffeine, amphetamine, mescaline, lysergic acid diethylamide (LSD), cannabis, chloral hydrate, theophylline, IBMX and others, have been studied on certain animals. It is believed that plants developed caffeine as a chemical defense against insects. [1]

  5. Cross-tolerance - Wikipedia

    en.wikipedia.org/wiki/Cross-tolerance

    Alcohol is another substance that often cross-tolerates with other drugs. Findings of cross-tolerance with nicotine in animal models suggest that it is also possible in humans, and may explain why the two drugs are often used together. [6] Numerous studies have also suggested the possibility of cross-tolerance between alcohol and cannabis. [7]

  6. Caffeinated alcoholic drink - Wikipedia

    en.wikipedia.org/wiki/Caffeinated_alcoholic_drink

    A caffeinated alcoholic drink is a drink that contains both alcohol (also known formally as ethanol) and a significant amount of caffeine. Caffeine, a stimulant, masks some of the depressant effects of alcohol. [1] However, in 2010 and 2011, this type of drink faced criticism for posing health risks to its drinkers.

  7. Polysubstance use - Wikipedia

    en.wikipedia.org/wiki/Polysubstance_use

    Alcohol and cocaine (for example coca wine) increase cardiovascular toxicity; [10] alcohol or depressant drugs, when taken with opioids, lead to an increased risk of overdose Opioids or cocaine taken with ecstasy or amphetamines also result in additional acute toxicity.

  8. Stimulant psychosis - Wikipedia

    en.wikipedia.org/wiki/Stimulant_psychosis

    Drugs in the class of amphetamines, or substituted amphetamines, are known to induce "amphetamine psychosis" typically when chronically abused or used in high doses. [8] In an Australian study of 309 active methamphetamine users, 18% had experienced a clinical level psychosis in the past year. [9]

  9. Paradoxical reaction - Wikipedia

    en.wikipedia.org/wiki/Paradoxical_reaction

    Amphetamines are a class of psychoactive drugs that are stimulants.Paradoxical drowsiness can sometimes occur in adults. [1] Research from the 1980s popularized the belief that ADHD stimulants such as amphetamine have a calming effect in individuals with ADHD, but opposite effects in the general population. [2]