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Following continued clinical research after the discovery of the effectiveness of HDE for breast cancer in 1944, HDE, most commonly with diethylstilbestrol and to a lesser extent ethinylestradiol, became the standard of care for the treatment of breast cancer in postmenopausal women from the early 1960s onwards. [1]
Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.
Observational studies of systemic HRT after breast cancer are generally reassuring. If HRT is necessary after breast cancer, estrogen-only therapy or estrogen therapy with a progestogen may be safer options than combined systemic therapy. [71] In women who are BRCA1 or BRCA2 mutation carriers, HRT does not appear to impact breast cancer risk. [72]
Olivia Munn, 43, says that breast cancer treatment put her into medically-induced menopause. She had four surgeries in 10 months, including a double mastectomy. Olivia Munn Says Breast Cancer ...
It is used as endocrine therapy for women with estrogen or progesterone receptor-positive, stage 4 or recurrent metastatic breast cancer [9] and has demonstrated similar efficacy compared to tamoxifen as adjuvant treatment of breast cancer and in the treatment of metastatic breast cancer. [8]
Olivia Munn is in medically induced menopause as a result of treatment to keep her breast cancer from recurring, the actress told People in an exclusive new interview. Munn, who last month ...
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