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A 2017 meta-analysis of people with heart failure taking 30–100 mg/d of CoQ 10 found a 31% lower mortality and increased exercise capacity, with no significant difference in the endpoints of left heart ejection fraction. [39] A 2021 meta-analysis found that coenzyme Q10 was associated with a 31% lower all-cause mortality in HF patients. [40]
Mortensen et al. hypothesize that the dosage (100 mg three times daily) and the formulation of the Q10 used in the Q-SYMBIO clinical trial may have resulted in the patients reaching a required "therapeutic threshold in serum and tissue of CoQ10" needed to reduce the number of major adverse cardiovascular events. [1]
Navas, López-Lluch and a team of researchers conducted a double-blind crossover study of the bioavailability of seven different Coenzyme Q10 formulations over a 48-hour period after ingestion of 100 mg. The researchers measured the Cmax and the area under the curve for each CoQ10 formulation in 14 healthy volunteers. They used a four-week ...
CoQ10. CoQ10 is a substance found in cells that helps convert food into energy. As an antioxidant, it has been linked to a reduction in the effects of aging on the skin and on a cellular level in ...
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This softgel, for example, packs in 300 mg of omega-3 and is certified by the National Science Foundation (NSF): Nature Made Fish Oil Supplements. $14.89 at amazon.com.