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Calcification of soft tissue (arteries, cartilage, heart valves, [1] [2] etc.) can be caused by vitamin K 2 deficiency or by poor calcium absorption due to a high calcium/vitamin D ratio. This can occur with or without a mineral imbalance. A common misconception is that calcification is caused by excess amount of calcium in diet. Dietary ...
Calcium deposits known as limbus sign may be visible in the eyes. [7] Symptoms are more common at high calcium blood values (12.0 mg/dL or 3 mmol/L). [6] Severe hypercalcaemia (above 15–16 mg/dL or 3.75–4 mmol/L) is considered a medical emergency: at these levels, coma and cardiac arrest can result.
Ectopic calcification is a pathologic deposition of calcium salts in tissues or bone growth in soft tissues.This can be a symptom of hyperphosphatemia.Formation of osseous tissue in soft tissues such as the lungs, eyes, arteries, or other organs is known as ectopic calcification, dystrophic calcification, or ectopic ossification.
In dystrophic calcification, basophilic calcium salt deposits aggregate, first in the mitochondria, then progressively throughout the cell. [citation needed] These calcifications are an indication of previous microscopic cell injury, occurring in areas of cell necrosis when activated phosphatases bind calcium ions to phospholipids in the membrane.
Osteo-odonto-keratoprosthesis (OOKP), also known as "tooth in eye" surgery, [1] is a medical procedure to restore vision in the most severe cases of corneal and ocular surface patients. It includes removal of a tooth from the patient or a donor.
Calcinosis is the formation of calcium deposits in any soft tissue. [1] It is a rare condition that has many different causes. These range from infection and injury to systemic diseases like kidney failure .
Metastatic calcinosis cutis is the consequence of calcium salts precipitating in normal tissue due to an underlying abnormality in the metabolism of phosphate and/or calcium. [2] Metastatic calcification can result from any systemic condition raising serum calcium and/or phosphate levels. Chronic renal failure is the most frequent underlying ...
The usual symptoms are pain and swelling of the affected salivary gland, both of which get worse when salivary flow is stimulated, e.g. with the sight, thought, smell or taste of food, or with hunger or chewing. This is often termed "mealtime syndrome." [2] Inflammation or infection of the gland may develop as a result.