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Geographic atrophy (GA), also known as atrophic age-related macular degeneration (AMD) or advanced dry AMD, is an advanced form of age-related macular degeneration that can result in the progressive and irreversible loss of retinal tissue (photoreceptors, retinal pigment epithelium, choriocapillaris) which can lead to a loss of central vision over time.
Avacincaptad pegol, sold under the brand name Izervay, is a medication used for the treatment of age-related macular degeneration. [1] Avacincaptad pegol is a complement inhibitor. [1] Avacincaptad pegol was approved for medical use in the United States in August 2023. [2] [3] [4]
Anecortave / æ n ə ˈ k ɔːr t eɪ v / is a novel angiogenesis inhibitor used in the treatment of the exudative (wet) form of age-related macular degeneration.Although similar in chemical structure to the corticosteroid hydrocortisone acetate, it possesses no glucocorticoid activity. [1]
Ranibizumab, sold under the brand name Lucentis among others, is a monoclonal antibody fragment created from the same parent mouse antibody as bevacizumab.It is an anti-angiogenic [16] that is approved to treat the "wet" type of age-related macular degeneration (AMD, also ARMD), diabetic retinopathy, and macular edema due to branch retinal vein occlusion or central retinal vein occlusion.
Treatment of AMD varies depending on the category of the disease at the time of diagnosis. In general, treatment is aimed at slowing down the progression of AMD. [69] As of 2018, there are no treatments to reverse the effects of AMD. [69] As of 2024, there are two drugs to dissolve the drusen in dry AMD, see below.
The approval opens up a wide market of patients for Lilly at a time when demand for Zepbound is already surging. Lilly's weight-loss treatment Zepbound becomes first FDA-approved drug for sleep ...
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