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Hakaru Hashimoto (橋本 策, Hashimoto Hakaru, May 5, 1881 – January 9, 1934) [1] [2] was a Japanese doctor and medical scientist of the Meiji and Taishō periods.He is best known for publishing the first description of the disease that was later named Hashimoto's thyroiditis.
The first gene locus associated with autoimmune thyroid disease was the major histocompatibility complex (MHC) region on chromosome 6p21. It encodes human leukocyte antigens (HLAs). Specific HLA alleles have a higher affinity to auto-antigenic thyroidal peptides and can contribute to autoimmune thyroid disease development.
A key difference is a malfunction of the innate immune system in autoinflammatory diseases, whereas in autoimmune diseases there is a malfunction of the adaptive immune system. [ 8 ] Symptoms of autoimmune diseases can significantly vary, primarily based on the specific type of the disease and the body part that it affects.
Most autoimmune diseases are sex-related; as a whole, women are much more likely to develop autoimmune disease than men. Being female is the single greatest risk factor for developing autoimmune disease than any other genetic or environmental risk factor yet discovered.
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...
Friedrich Wegener (7 April 1907, Varel – 9 July 1990, Lübeck, [veːɡɐnəɐ̯]) was a German pathologist who is notable for being a high-ranking Nazi physician and for his description of a rare disease originally referred to Wegener disease and now referred to as granulomatosis with polyangiitis. Although this disease was known before ...
Disease Discoverer 2600 BC: Malaria [1] 1900 BC: Rabies: 1600 BC: Cancer: Hippocrates: ca 300: Dengue: Jin Dynasty (266–420) 9th century: Measles: Muhammad ibn Zakariya al-Razi: 14th century: African trypanosomiasis: First described by Arab traders [2] 1798: Color blindness: John Dalton: 1798: Amyotrophic lateral sclerosis: John Dalton: 1881 ...
This discovery led to the understanding of what is now known as autoimmune diseases. [169] To ensure that the person has lupus and not another autoimmune disease, the American College of Rheumatology (ACR) established a list of clinical and immunologic criteria that, in any combination, point to SLE. The criteria include symptoms that the ...