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Ablysinol (a brand of 99% ethanol medical alcohol) was sold from $1,300 to $10,000 per 10-pack [Give volume amount please] in 2020 due to FDA administrator action granting exclusivity when used for treating hypertrophic obstructive cardiomyopathy with alcohol septal ablation in the US through 2025, despite "misuse" of the orphan drug act.
Salbutamol, also known as albuterol and sold under the brand name Ventolin among others, [1] is a medication that opens up the medium and large airways in the lungs. [8] It is a short-acting β 2 adrenergic receptor agonist that causes relaxation of airway smooth muscle . [ 8 ]
Ethanol does not bind to plasma proteins or other biomolecules. [13] [2] [3] The rate of distribution depends on blood supply, [4] specifically the cross-sectional area of the local capillary bed and the blood flow per gram of tissue. [13] As such, ethanol rapidly affects the brain, liver, and kidneys, which have high blood flow. [2]
Albuterol (Salbutamol) Has N-t-butyl and a salicyl alcohol phenyl ring which gives it optimal β2-selectivity. [14] Salbutamol is a short-acting β2-agonist, but has a rapid onset of action. [18] Its onset by inhalation is within 5 minutes. The hydroxyl group on the β-carbon is a mixture of S- and R-isomers, where the R-isomer is the active one.
Ipratropium bromide/salbutamol, sold under the brand name Combivent among others, is a combination medication used to treat chronic obstructive pulmonary disease (COPD). [1] [4] [5] It contains ipratropium (an anticholinergic) and salbutamol (albuterol, a β 2-adrenergic agonist).
An inhaler (puffer, asthma pump or allergy spray) is a medical device used for delivering medicines into the lungs through the work of a person's breathing. This allows medicines to be delivered to and absorbed in the lungs, which provides the ability for targeted medical treatment to this specific region of the body, as well as a reduction in the side effects of oral medications.
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