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Emodepside is an anthelmintic drug that is effective against a number of gastrointestinal nematodes, is licensed for use in cats [1] and belongs to the class of drugs known as the octadepsipeptides, [2] a relatively new class of anthelmintic (research into these compounds began in the early 1990s), [3] which are suspected to achieve their anti-parasitic effect by a novel mechanism of action ...
B.T. was established in 1916 [4] as a tabloid spinoff from Berlingske Tidende. [5] The paper is based in Copenhagen. [4] A large, red neon sign displays the company's logo at the Trianglen square in the Østerbro district of Copenhagen. B.T. is part of Berlingske Media Group. [4] It had a conservative stance in the 1960s. [6] B.T. 'modernized ...
Remdesivir and GS-441524 were both found to be effective in vitro against feline coronavirus strains responsible for feline infectious peritonitis (FIP), a lethal systemic disease affecting domestic cats. Remdesivir was never tested in cats (though some vets now offer it [1]), but GS-441524 has been found to be effective treatment for FIP.
[5] [18] It binds to plasma proteins at a rate of 99.5%; it has a low volume of distribution (9 L/kg) and is thus not extensively absorbed. [5] [10] Subcutaneously administered maropitant had peak plasma concentration around half an hour after administration; the mean half-life is 6–8 hours, and a single dose lasts 24 hours in dogs. [10]
Butorphanol exhibits partial agonist and antagonist activity at the μ-opioid receptor, as well as partial agonist activity at the κ-opioid receptor (K i = 2.5 nM; EC 50 = 57 nM; E max = 57%). [ 8 ] [ 9 ] Stimulation of these receptors on central nervous system neurons causes an intracellular inhibition of adenylate cyclase , closing of influx ...
Pet Supplies Plus was founded in 1988 by Harry Shallop and Jack Berry, in Redford, Michigan. [8] In December 2018, Pet Supplies Plus was acquired by Sentinel Capital Partners. [9] In January 2021, the Franchise Group, Inc., announced it was acquiring Pet Supplies Plus, [10] [11] and the deal was closed on March 10, 2021. [12]