Search results
Results From The WOW.Com Content Network
As a consequence of the biochemical reactions in which homocysteine is involved, deficiencies of vitamin B 6, folic acid (vitamin B 9), and vitamin B 12 can lead to high homocysteine levels. [2] Other possible causes of hyperhomocysteinemia include genetics, excessive methionine intake, and other diseases. [3]
Vitamin B 12 deficiency, also known as cobalamin deficiency, is the medical condition in which the blood and tissue have a lower than normal level of vitamin B 12. [5] Symptoms can vary from none to severe. [1] Mild deficiency may have few or absent symptoms. [1]
"B12" and "Cbl" redirect here. For other uses of B12, see B12 (disambiguation). For the musical group, see Carbon Based Lifeforms. Pharmaceutical compound Vitamin B12 General skeletal formula of cobalamins Stick model of cyanocobalamin (R = CN) based on the crystal structure Clinical data Other names Vitamin B12, vitamin B-12, cobalamin AHFS / Drugs.com Monograph MedlinePlus a605007 License ...
MyKind Organics Vegan B12 Spray. Made with methylcobalamin and oodles of organic fruit and botanicals, one spray a day tastes like raspberries while delivering 500 micrograms of vitamin B12. Plus ...
The resulting elevated concentrations of homocysteine and MMA are often found in patients with low serum vitamin B 12 and can usually be lowered with successful vitamin B 12 replacement therapy. However, elevated MMA and homocysteine concentrations may persist in patients with cobalamin concentrations between 200 and 350 pg/mL. [ 23 ]
An increase in both MMA and homocysteine distinguishes B 12 deficiency from folate deficiency because homocysteine alone increases in the latter. [ 57 ] [ 58 ] Elevated gastrin levels can be found in around 80–90% of PA cases, but they may also be found in other forms of gastritis.
Conversion of homocysteine to methionine requires folate and vitamin B 12. Elevated plasma homocysteine and low folate are associated with cognitive impairment, dementia and Alzheimer's disease. [62] [63] Supplementing the diet with folic acid and vitamin B 12 lowers plasma homocysteine. [63]
In the body, homocysteine can be recycled into methionine or converted into cysteine with the aid of vitamin B 6, B 9, and B 12. [3] High levels of homocysteine in the blood (hyperhomocysteinemia) is regarded as a marker of cardiovascular disease, likely working through atherogenesis, which can result in ischemic injury.