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The Ervebo vaccine, developed by Merck, is a single-dose vaccine. It works by using a modified virus to produce antibodies against Ebola, equipping the immune system to recognise and neutralise ...
The Centers for Disease Control and Prevention (CDC) is urging healthcare workers in the U.S. to consider Ebola when patients have symptoms, while airport officials are also screening passengers ...
Many Ebola vaccine candidates had been developed in the decade before 2014, but none has yet been approved for clinical use in humans. [211] Several promising vaccine candidates have been shown to protect nonhuman primates (usually macaques) against lethal infection, and some are now going through the clinical trial process. [212] [213]
The 2018 Équateur province Ebola outbreak occurred in the north-west of the Democratic Republic of the Congo (DRC) from May to July 2018. It was contained entirely within Équateur province, and was the first time that vaccination with the rVSV-ZEBOV Ebola vaccine had been attempted in the early stages of an Ebola outbreak, [6] with a total of 3,481 people vaccinated.
A number of companies were expected to develop Ebola vaccines: GlaxoSmithKline, NewLink Genetics, Johnson & Johnson, and Bavarian Nordic. [82] Another company, Emergent BioSolutions, was a contestant for manufacturing new doses of ZMapp, [citation needed] a drug for Ebola virus disease treatment originally developed by Mapp Biopharmaceutical. [83]
A stockpile of half-a-million Ebola vaccine doses was established by Gavi and other global health partners in 2019 for use in outbreaks of haemorrhagic fever, which has an average fatality rate of ...
In April 2019, following a large-scale ring-vaccination scheme in the DRC outbreak, the WHO published the preliminary results of its research, in association with the DRC's Institut National pour la Recherche Biomedicale, into the effectiveness of the ring vaccination program, stating that the rVSV-ZEBOV-GP vaccine had been 97.5% effective at stopping Ebola transmission, relative to no ...
In fact, the nature of Ebola - which is spread by close contact with bodily fluids and blood - means that any modern hospital using standard, rigorous, infection-control measures should be able to ...