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Macular hard drusen in the right eye. 65-year-old diabetic woman. Drusen, from the German word for node or geode (singular, "Druse"), are tiny yellow or white accumulations of extracellular material that build up between Bruch's membrane and the retinal pigment epithelium of the eye. The presence of a few small ("hard") drusen is normal with ...
Treatment of AMD varies depending on the category of the disease at the time of diagnosis. In general, treatment is aimed at slowing down the progression of AMD. [69] As of 2018, there are no treatments to reverse the effects of AMD. [69] As of 2024, there are two drugs to dissolve the drusen in dry AMD, see below.
Drugs such as tropicamide are used in medicine to permit examination of the retina and other deep structures of the eye. Mydriatics typically also have a cycloplegic effect, reducing or paralyzing the accommodation reflex which may also be used for certain ophthalmic examinations or treatments, such as reducing painful ciliary muscle spasm.
Intravitreal injection is the method of administration of drugs into the eye by injection with a fine needle. The medication will be directly applied into the vitreous humor. [1] It is used to treat various eye diseases, such as age-related macular degeneration (AMD), diabetic retinopathy, and infections inside the eye such as endophthalmitis. [1]
Tropicamide, sold under the brand name Mydriacyl among others, is a medication used to dilate the pupil and help with examination of the eye. [3] Specifically it is used to help examine the back of the eye. [4] It is applied as eye drops. [3] Effects occur within 40 minutes and last for up to a day. [3]
Botulinum toxin is the most acutely lethal toxin that is known. It is produced by the bacterium clostridium botulinum.It acts inside nerve terminals by decreasing the release of acetylcholine, blocking neuromuscular transmission and thereby causing flaccid muscular paralysis.
The optic nerve head, or optic disc is the anterior end of the nerve that is in the eye and hence is visible with an ophthalmoscope. It is located nasally and slightly inferior to the macula of the eye. There is a blind spot at the optic disc because there are no rods or cones beneath it to detect light.
Micrograph of heart muscle showing lipofuscin pigment, H&E stain. Lipofuscin accumulation in the eye, is a major risk factor implicated in macular degeneration, a degenerative disease, [15] and Stargardt disease, an inherited juvenile form of macular degeneration.