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Azacitidine is a chemical analogue of the nucleoside cytidine, which is present in DNA and RNA.It is thought to have antineoplastic activity via two mechanisms – at low doses, by inhibiting of DNA methyltransferase, causing hypomethylation of DNA, [16] and at high doses, by its direct cytotoxicity to abnormal hematopoietic cells in the bone marrow through its incorporation into DNA and RNA ...
Decitabine (i.e., 5-aza-2′-deoxycytidine), sold under the brand name Dacogen among others, acts as a nucleic acid synthesis inhibitor. [4] It is a medication for the treatment of myelodysplastic syndromes , a class of conditions where certain blood cells are dysfunctional, and for acute myeloid leukemia (AML). [ 5 ]
Map of the USA showing borders of states and counties. Adapted by Wapcaplet from a public-domain map courtesy of the U.S. Census Bureau website. Date: 25 September 2006: Source: en:File:Map of USA with county outlines.png: Author
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The median price increase of the drugs being hiked Jan. 1 is 4.5%, which is in line with the median for all price increases last year. Drugmakers to raise US prices on over 250 medicines starting ...
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Image:Map of USA-bw.png – Black and white outlines for states, for the purposes of easy coloring of states. Image:BlankMap-USA-states.PNG – US states, grey and white style similar to Vardion's world maps. Image:Map of USA with county outlines.png – Grey and white map of USA with county outlines.
The weight loss drug Zepbound, generically known as tirzepatide, is also now an approved medication to treat obstructive sleep apnea, per a Food and Drug Administration Dec. 20 press release.. The ...