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Elevations threefold greater than normal were recorded in 0.5% of people treated with atorvastatin 10 mg-80 mg rather than placebo. [68] Usage instructions in package inserts for this statin define the requirement that hepatic function be assessed with laboratory tests before beginning atorvastatin treatment and repeated periodically as ...
With the recent elucidation of the structures of the catalytic portion of human HMGR enzyme complexed with six different statins by a series of crystallography studies, new possibilities have opened up for the rational design and optimization of even better HGMR inhibitors.
The best-selling statin is atorvastatin, also known as Lipitor, which in 2003 became the best-selling pharmaceutical in history. [12] The manufacturer Pfizer reported sales of US$12.4 billion in 2008. [13] Patient compliance with statin usage is problematic despite robust evidence of the benefits. [14] [15]
Dyslipidemia. Dyslipidemia is when the lipids in your blood are too high or too low. Estimates suggest that 53 percent of adults in the U.S. have lipid abnormalities.. Lipids are a type of fat ...
Atherosclerosis: Overview. This article was reviewed by Craig Primack, MD, FACP, FAAP, FOMA. Atherosclerosis happens when a fatty substance called plaque builds up inside your arteries.
Actor and playwright Harvey Fierstein is sharing how he lost 120 pounds. The 70-year-old told Page Six that his weight has always fluctuated, and weight loss medication, he added, has helped him ...
For example, some may lower low density lipoprotein (LDL) levels more so than others, while others may preferentially increase high density lipoprotein (HDL). Clinically, the choice of an agent depends on the patient's cholesterol profile , cardiovascular risk , and the liver and kidney functions of the patient, evaluated against the balancing ...
They also make a great addition to salads, soups, casseroles and more. 2. Low-Fat Dairy. Low-fat dairy is another category of high-protein options that are easy to use and found at a reasonable price.
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