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Laboratory synthesized sulfanilamide. Sulfanilamide is a yellowish-white or white crystal or fine powder. It has a density of 1.08 g/cm 3 and a melting point of 164.5-166.5 °C. The pH of a 0.5% aqueous solution of Sulfanilamide is 5.8 to 6.1. It has a λ max of 255 and 312 nm. [5]
In this example, the reactants are aniline, triethylamine (Et 3 N, Et = ethyl group), and iodine. Sulfur dioxide is believed to be activated through a series of intermediates: Et 3 N− + −I −, Et 3 N−I + −I − 3 and Et 3 N + −SO − 2. The sulfamide functional group is an increasingly common structural feature used in medicinal ...
Skeletal structural formula of Vitamin B 12.Many organic molecules are too complicated to be specified by a molecular formula.. The structural formula of a chemical compound is a graphic representation of the molecular structure (determined by structural chemistry methods), showing how the atoms are connected to one another. [1]
Chemical structure of a generic acylsulfonamide. Acylsulfonamide is a functional group in organic chemistry that is sometimes used in medicinal chemistry. [1] It consists of a sulfonamide group (SO 2 NH) linked to an acyl group (RCO), forming the structure R 1-CO-NH-SO 2-R 2.
In organosulfur chemistry, sulfinamide is a functional group with the structure R−S(O)−NR 2 (where R = alkyl or aryl). [1] This functionality is composed of a sulfur - carbon ( S−C ) single bond , a sulfur- nitrogen ( S−N ) single bond , and a sulfur-oxygen (S-O) bond (see Sulfoxide for the nature of this bond) [ 2 ] .
General chemical structure of a sulfanilide. In organic chemistry, a sulfonanilide group is a functional group found in certain organosulfur compounds.It possesses the chemical structure R−S(=O) 2 −N(−C 6 H 5)−R', and consists of a sulfonamide group (R−S(=O) 2 −NR'R") where one of the two nitrogen substituents (R' or R") is a phenyl group (C 6 H 5).
Many important drugs contain the sulfonamide group. [1] A sulfonamide (compound) is a chemical compound that contains this group. The general formula is R−SO 2 NR'R" or R−S(=O) 2 −NR'R", where each R is some organic group; for example, "methanesulfonamide" (where R = methane, R' = R" = hydrogen) is CH 3 SO 2 NH 2.
Sulfonyl groups can be written as having the general formula R−S(=O) 2 −R′, where there are two double bonds between the sulfur and oxygen. [1]: 53 [2] Sulfonyl groups can be reduced to the sulfide with diisobutylaluminium hydride (DIBALH). Lithium aluminium hydride (LiAlH 4) reduces some but not all sulfones to sulfides. [1]: 1851