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  2. ABC transporter - Wikipedia

    en.wikipedia.org/wiki/ABC_transporter

    The ABC transporters, ATP synthase (ATP)-binding cassette transporters are a transport system superfamily that is one of the largest and possibly one of the oldest gene families. It is represented in all extant phyla, from prokaryotes to humans. [1] [2] [3] ABC transporters belong to translocases.

  3. ABCA1 - Wikipedia

    en.wikipedia.org/wiki/ABCA1

    ATP-binding cassette transporter ABCA1 (member 1 of human transporter sub-family ABCA), also known as the cholesterol efflux regulatory protein (CERP) is a protein which in humans is encoded by the ABCA1 gene. [5] This transporter is a major regulator of cellular cholesterol and phospholipid homeostasis.

  4. ATP-binding domain of ABC transporters - Wikipedia

    en.wikipedia.org/wiki/ATP-binding_domain_of_ABC...

    ABC transporters are minimally constituted of two conserved regions: a highly conserved ATP binding cassette (ABC) and a less conserved transmembrane domain (TMD). These regions can be found on the same protein or on two different ones. Most ABC transporters function as a dimer and therefore are constituted of four domains, two ABC modules and ...

  5. ABCC1 - Wikipedia

    en.wikipedia.org/wiki/ABCC1

    The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).

  6. Transmembrane domain of ABC transporters - Wikipedia

    en.wikipedia.org/wiki/Transmembrane_domain_of...

    ABC transporter transmembrane domain is the main transmembrane structural unit of ATP-binding cassette transporter proteins, consisting of six alpha helixes that traverse the plasma membrane. Many members of the ABC transporter family ( Pfam PF00005 ) have two such regions.

  7. ABCF1 - Wikipedia

    en.wikipedia.org/wiki/ABCF1

    ATP-binding cassette sub-family F member 1 is a protein that in humans is encoded by the ABCF1 gene. [5] [6] The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct ...

  8. Multidrug resistance-associated protein 2 - Wikipedia

    en.wikipedia.org/wiki/Multidrug_resistance...

    MRP2 is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).

  9. TAP1 - Wikipedia

    en.wikipedia.org/wiki/TAP1

    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).