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Mebendazole is usually well tolerated. [5] Common side effects include headache, vomiting, and ringing in the ears. [5] If used at large doses it may cause bone marrow suppression. [5] It is unclear if it is safe in pregnancy. [5] [2] Mebendazole is a broad-spectrum antihelminthic agent of the benzimidazole type. [5]
A single 100 milligram dose of mebendazole with one repetition after two weeks, is considered the safest, and is usually effective with cure rate of 96%. [8] [26] Mebendazole has no serious side effects, although abdominal pain and diarrhea have been reported. [26]
Mebendazole (Vermox), causes slow immobilization and death of the worms by selectively and irreversibly blocking uptake of glucose and other nutrients in susceptible adult intestine where helminths dwell. Oral dosage is 100 mg every 12 hours for 3 days. [citation needed]
Albendazole is a broad-spectrum antihelmintic and antiprotozoal agent of the benzimidazole type. [3] It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases.
A 2008 review found that the efficacy of single-dose treatments for hookworm infections were as follows: 72% for albendazole, 15% for mebendazole, and 31% for pyrantel pamoate. [29] This substantiates prior claims that albendazole is much more effective than mebendazole for hookworm infections.
Side effects include nausea, headache, dizziness, trouble sleeping, and rash. [2] A lower dose should be used in people with liver disease. [2] While it does not appear to be harmful during pregnancy, it has not been studied for this use. [3] It is unclear if it is safe for use during breastfeeding. [2] It is in the antihelmintic family of ...
The evidence for comparing metronidazole to other alternatives such as mebendazole, tinidazole, or nitazoxanide was felt to be of very low quality. [60] While tinidazole has side effects and efficacy similar to those of metronidazole, it is administered with a single dose. [20]
Mass deworming of children can be carried out by administering mebendazole and albendazole which are two types of anthelmintic drug. [5] The cost of providing one tablet every six to twelve months per child (typical doses) is relatively low. [6] Soil-transmitted helminthiasis is the most prevalent neglected tropical disease. [7]
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