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  2. Carbonic anhydrase - Wikipedia

    en.wikipedia.org/wiki/Carbonic_anhydrase

    The enzyme maintains acid-base balance and helps ... and tissues because the pKa is close to the physiological pH = 7.2 – 7.6. Since HCO 3 ... 3.1 × 10 5: 41 ...

  3. Bicarbonate buffer system - Wikipedia

    en.wikipedia.org/wiki/Bicarbonate_buffer_system

    3), and carbon dioxide (CO 2) in order to maintain pH in the blood and duodenum, among other tissues, to support proper metabolic function. [1] Catalyzed by carbonic anhydrase, carbon dioxide (CO 2) reacts with water (H 2 O) to form carbonic acid (H 2 CO 3), which in turn rapidly dissociates to form a bicarbonate ion (HCO −

  4. Acid–base homeostasis - Wikipedia

    en.wikipedia.org/wiki/Acid–base_homeostasis

    [13] [16] [17] [18] [1] The normal pH in the fetus differs from that in the adult. In the fetus, the pH in the umbilical vein pH is normally 7.25 to 7.45 and that in the umbilical artery is normally 7.18 to 7.38. [19] Aqueous buffer solutions will react with strong acids or strong bases by absorbing excess H + ions, or OH −

  5. Intracellular pH - Wikipedia

    en.wikipedia.org/wiki/Intracellular_pH

    3). Physiologically normal intracellular pH is most commonly between 7.0 and 7.4, though there is variability between tissues (e.g., mammalian skeletal muscle tends to have a pH i of 6.8–7.1). [4] [5] There is also pH variation across different organelles, which can span from around 4.5 to 8.0. [6] [7] pH i can be measured in a number of ...

  6. Plasma membrane H+-ATPase - Wikipedia

    en.wikipedia.org/wiki/Plasma_membrane_H+-ATPase

    Intracellular pH regulation. Intracellular pH remains constant during cell growth, it is presumed, to ensure optimal activity of the cytoplasmic enzymes. This is controlled by the proton pump. Acid growth. Acidification of the external medium caused by activation of the plasma membrane H +-ATPase initiates cellular expansion.

  7. Acid hydrolase - Wikipedia

    en.wikipedia.org/wiki/Acid_hydrolase

    An acid hydrolase is an enzyme that works best at acidic pHs.It is commonly located in lysosomes, which are acidic on the inside.Acid hydrolases may be nucleases, proteases, glycosidases, lipases, phosphatases, sulfatases and phospholipases and make up the approximately 50 degradative enzymes of the lysosome that break apart biological matter.

  8. Glycerol-3-phosphate dehydrogenase - Wikipedia

    en.wikipedia.org/wiki/Glycerol-3-phosphate_de...

    Glycerol-3-phosphate dehydrogenase (GPDH) is an enzyme that catalyzes the reversible redox conversion of dihydroxyacetone phosphate (a.k.a. glycerone phosphate, outdated) to sn-glycerol 3-phosphate. [2] Glycerol-3-phosphate dehydrogenase serves as a major link between carbohydrate metabolism and lipid metabolism.

  9. Enolase - Wikipedia

    en.wikipedia.org/wiki/Enolase

    The systematic name of this enzyme is 2-phospho-D-glycerate hydro-lyase (phosphoenolpyruvate-forming). The reaction is reversible, depending on environmental concentrations of substrates. [3] The optimum pH for the human enzyme is 6.5. [4] Enolase is present in all tissues and organisms capable of glycolysis or fermentation.