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Dimethoxytrityl, often abbreviated DMT, is a protecting group widely used for protection of the 5'-hydroxy group in nucleosides, particularly in oligonucleotide synthesis. [1] It is usually bound to a molecule, but can exist as a stable cation in solution, where it appears bright orange. [2]
Orthogonal protection is a strategy allowing the specific deprotection of one protective group in a multiply-protected structure. For example, the amino acid tyrosine could be protected as a benzyl ester on the carboxyl group, a fluorenylmethylenoxy carbamate on the amine group, and a tert -butyl ether on the phenol group.
Later analysis tentatively found 5-MeO-DMT in stems, leaves and roots; DMT, NMT and 5-MeO-DMT were tentatively observed in seeds, but follow-up tests were negative. [ 9 ] [ 53 ] Bark contains unidentified alkaloids [ 54 ] Bark in one sample subsequently found to contain an alkaloid which has an Rf value suggesting DMT.
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6-MeO-DMT, or 6-methoxy-N,N-dimethyltryptamine, also known as 6-OMe-DMT, is a serotonergic drug of the tryptamine family. [ 1 ] [ 2 ] It is the 6- methoxy derivative of the serotonergic psychedelic N , N -dimethyltryptamine (DMT) and is a positional isomer of the serotonergic psychedelic 5-MeO-DMT .
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