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Laryngopharyngeal reflux; Other names: Extraesophageal reflux disease (EERD), [1] Silent reflux, [2] and Supra-esophageal reflux [3] Sagittal illustration of the anterior portion of the human head and neck. In LPR, the pharynx (1), oropharynx (2) and larynx (3) are exposed to gastric contents that flow upward through the esophagus (4). Specialty
Laryngopharyngeal reflux is considered to be a risk factor for development of hypopharyngeal cancer. [6] Such reflux frequently contains bile acids , and bile acid presence in the upper aerodigestive tract is associated with inflammation , DNA damage and neoplastic changes .
For example, people with acid reflux disease, especially those with Throatburn Reflux usually have swollen vocal cords due to years of acid damage. Untreated acid-injured vocal cords will not have as sharp reflexes as vocal cords that are not swollen. Therefore, aspiration is common in people with chronic acid reflux disease.
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Laryngeal cancer may spread by: direct extension to adjacent structures, metastasis to regional cervical lymph nodes, or via the blood stream. The most common site of distant metastases is the lung. Laryngeal cancer occurred in 177,000 people in 2018, and resulted in 94,800 deaths (an increase from 76,000 deaths in 1990).
Other causes of chest pain such as heart disease should be ruled out before making the diagnosis. [42] Another kind of acid reflux, which causes respiratory and laryngeal signs and symptoms, is called laryngopharyngeal reflux (LPR) or extraesophageal reflux disease (EERD).
Acid reflux can bring on some (unwelcome) surprises. Home & Garden. Medicare
A hiatal hernia or hiatus hernia [2] is a type of hernia in which abdominal organs (typically the stomach) slip through the diaphragm into the middle compartment of the chest. [1] [3] This may result in gastroesophageal reflux disease (GERD) or laryngopharyngeal reflux (LPR) with symptoms such as a taste of acid in the back of the mouth or heartburn.