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Loratadine, sold under the brand name Claritin among others, is a medication used to treat allergies. [5] This includes allergic rhinitis (hay fever) and hives . [ 5 ] It is also available in drug combinations such as loratadine/pseudoephedrine , in which it is combined with pseudoephedrine , a nasal decongestant . [ 5 ]
In 2020, the UK National Health Service wrote that "[m]ost people can safely take antihistamines" but that "[s]ome antihistamines may not be suitable" for young children, the pregnant or breastfeeding, for those taking other medicines, or people with conditions "such as heart disease, liver disease, kidney disease or epilepsy".
Nephrotoxicity is toxicity in the kidneys. It is a poisonous effect of some substances, both toxic chemicals and medications, on kidney function. [1] There are various forms, [2] and some drugs may affect kidney function in more than one way. Nephrotoxins are substances displaying nephrotoxicity.
Pseudoephedrine is excreted primarily via the kidneys in urine. [1] [11] Its urinary excretion is highly influenced by urinary pH and is decreased when the urine is acidic and is increased when it is alkaline. [1] [11] [58] The elimination half-life of pseudoephedrine on average is 5.4 hours [2] and ranges from 3 to 16 hours depending on ...
(Reuters) -The U.S. Food and Drug Administration has approved the use of Novartis' drug to reduce excess protein in the urine of patients with a type of kidney disease, the health regulator's ...
There is evidence supporting its use for allergies, but second generation antihistamines such as ketotifen and loratadine have shown equal results with fewer side effects. [9] It is also used as a preventive treatment against migraine. In a 2013 study the frequency of migraine was dramatically reduced in patients within 7 to 10 days after ...
Fortunately, long-term data from organ donors has shown that their kidney function tends to remain stable and the risk of developing chronic kidney disease is only slightly higher than in those ...
Among second-generation antihistamines, cetirizine is more likely than fexofenadine and loratadine to cause drowsiness. [7] Use in pregnancy appears safe, but use during breastfeeding is not recommended. [8] The medication works by blocking histamine H 1 receptors, mostly outside the brain. [6] Cetirizine can be used for paediatric patients.