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  2. Do doctors still recommend aspirin? Yes, but it's complicated.

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    Nearly one in three Americans over the age of 60 — roughly 19 million people — take aspirin daily, according to a 2021 study in the Annals of Internal Medicine. And more than three million ...

  3. Daily low-dose aspirin has its benefits — and risks. Here's ...

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    For years, doctors recommended that older adults at a higher risk for heart attack or stroke take a low-dose aspirin once a day to lower their risk.

  4. Many older adults are still taking daily aspirin, even though ...

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    A separate survey conducted last year by researchers at the University of Michigan found that about 1 in 4 adults surveyed, ages 50 to 80, reported taking aspirin regularly, around three or more ...

  5. Aspirin - Wikipedia

    en.wikipedia.org/wiki/Aspirin

    For some people, aspirin does not have as strong an effect on platelets as for others, an effect known as aspirin-resistance or insensitivity. One study has suggested women are more likely to be resistant than men, [157] and a different, aggregate study of 2,930 people found 28% were resistant. [158]

  6. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    Many charts derive their data from studies conducted on opioid-naive patients. Patients with chronic (rather than acute) pain may respond to analgesia differently. Repeated administration of a medication is also different from single dosing, as many drugs have active metabolites that can build up in the body. [ 6 ]

  7. Pharmacodynamics - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics

    In recreational psychoactive drug spaces, duration refers to the length of time over which the subjective effects of a psychoactive substance manifest themselves. Duration can be broken down into 6 parts: (1) total duration (2) onset (3) come up (4) peak (5) offset and (6) after effects.

  8. Many Older Adults Take Daily Aspirin to Cut Cardiovascular ...

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    Many Americans 60 years and older still take daily aspirin to help prevent cardiovascular disease, even though it can pose significant health risks. ... for adults 70 and older, 38% are still ...

  9. Mechanism of action of aspirin - Wikipedia

    en.wikipedia.org/wiki/Mechanism_of_action_of_aspirin

    Aspirin acts as an acetylating agent where an acetyl group is covalently attached to a serine residue in the active site of the COX enzyme. [1] This makes aspirin different from other NSAIDs (such as diclofenac and ibuprofen), which are reversible inhibitors; aspirin creates an allosteric change in the structure of the COX enzyme. [2]