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Emamectin is the 4″-deoxy-4″-methylamino derivative of abamectin, a 16-membered macrocyclic lactone produced by the fermentation of the soil actinomycete Streptomyces avermitilis. [ 1 ] [ 2 ] It is generally prepared as the salt with benzoic acid , emamectin benzoate, which is a white or faintly yellow powder. [ 3 ]
Abamectin (also called avermectin B 1) is a widely used insecticide and anthelmintic.Abamectin, is a member of the avermectin family and is a natural fermentation product of soil dwelling [1] actinomycete Streptomyces avermitilis. [2]
They show activity against a broad range of nematodes and arthropod parasites of domestic animals at dose rates of 300 μg/kg or less (200 μg/kg ivermectin appearing to be the common interspecies standard, from humans to horses to house pets, unless otherwise indicated).
PRL-8-53 is relatively non-toxic, with an oral LD 50 in mice of 860 mg/kg, giving the drug a high therapeutic index. Doses above 8 mg/kg have brief hypotensive effects in canines. High doses depress motor activity in the rat and mouse, with the ED 50 for a 50% reduction in motor activity of mice at 160 mg/kg.
Benzyl benzoate is an organic compound which is used as a medication and insect repellent. [1] As a medication it is used to treat scabies and lice . [ 2 ] For scabies either permethrin or malathion is typically preferred. [ 3 ]
Potassium benzoate (E212), the potassium salt of benzoic acid, is a food preservative that inhibits the growth of mold, yeast and some bacteria. It works best in low- pH products, below 4.5, where it exists as benzoic acid.