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Smoke inhalation injury, either by itself but more so in the presence of body surface burn, can result in severe lung-induced morbidity and mortality. [3] The most common cause of death in burn centers is now respiratory failure.
Smoke inhalation is the breathing in of harmful fumes (produced as by-products of combusting substances) through the respiratory tract. [1] This can cause smoke inhalation injury (subtype of acute inhalation injury) which is damage to the respiratory tract caused by chemical and/or heat exposure, as well as possible systemic toxicity after smoke inhalation.
Most (69%) burn injuries occur at home or at work (9%), [15] and most are accidental, with 2% due to assault by another, and 1–2% resulting from a suicide attempt. [25] These sources can cause inhalation injury to the airway and/or lungs, occurring in about 6%. [4] Burn injuries occur more commonly among the poor. [25]
Causes may include sepsis, pancreatitis, trauma, pneumonia, and aspiration. [1] The underlying mechanism involves diffuse injury to cells which form the barrier of the microscopic air sacs of the lungs, surfactant dysfunction, activation of the immune system, and dysfunction of the body's regulation of blood clotting. [5]
It can result from blunt or penetrating trauma to the neck or chest, [3] inhalation of harmful fumes or smoke, or aspiration of liquids or objects. [4] Though rare, TBI is a serious condition; it may cause obstruction of the airway with resulting life-threatening respiratory insufficiency. [2] Other injuries accompany TBI in about half of cases ...
Inhalation of toxic materials can also cause serious injury to the respiratory tract. [21] Severe trauma to the chest can cause damage to the lungs, including pulmonary contusions, accumulation of blood, or a collapsed lung. The inflammation response to a lung injury can cause acute
Cole Schmidtknecht, 22, couldn't pay for his daily inhaler due to the “prohibitively expensive” price increase, but then he died of an asthma attack, per a lawsuit filed by his parents
Besides causing silicosis, inhalation of silica can cause or exacerbate COPD. It can also impair lung function in general and cause cancer by oxidation damage. It is classified as a "known human carcinogen" (Group 1 carcinogen) by the IARC. Exposure is common for people working in tunneling, quarrying, construction, sandblasting, roadway repair ...