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Illustration depicting ankylosing spondylitis. The signs and symptoms of ankylosing spondylitis often appear gradually, with peak onset between 20 and 30 years of age. [11] Initial symptoms are usually a chronic dull pain in the lower back or gluteal region combined with stiffness of the lower back. [12]
Since the disease ankylosing spondylitis was still defined by the Modified New York criteria of 1984, there was the need to find a new disease term that would also include the less severe forms or early onset of ankylosing spondylitis. This expression was found in the umbrella term axial spondyloarthritis.
People with ankylosing spondylitis experience up to 50% more sick leave episodes, an overall 8% loss of productivity, and a thrice higher rate of disability than the general population. Their overall frequency of disability and economic costs are comparable to those of rheumatoid arthritis. [48]
721.6 Ankylosing vertebral hyperostosis; 721.7 Traumatic spondylopathy; 722 Intervertebral disc disorders. 722.0 Displacement cervical intervertebral disc; 722.1 Lumbar disc displacement w/o myelopathy; 722.2 Degeneration of intervertebral disc site unspecified; 722.3 Schmorl's nodes; 722.4 Degenerative disc disease, cervical
The BASDAI or Bath Ankylosing Spondylitis Disease Activity Index is a validated diagnostic test which allows a physician, usually a rheumatologist, to determine the effectiveness of a current drug therapy, or the need to institute a new drug therapy for the treatment of Ankylosing spondylitis (AS).
Spondylitis is an inflammation of the vertebrae. It is a form of spondylopathy . In many cases, spondylitis involves one or more vertebral joints , as well, which itself is called spondylarthritis .
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