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Taking the example of sickle-cell disease, in an emergency room, knowing the geographic origin of a patient may help a doctor doing an initial diagnosis if a patient presents with symptoms compatible with this disease. This is unreliable evidence with the disease being present in many different groups as noted above with the trait also present ...
The most well-known examples of genetically determined disorders that vary in incidence between ethnic groups would be sickle cell disease and thalassemia among black and Mediterranean populations respectively and Tay–Sachs disease among people of Ashkenazi Jewish descent. Some fear that the use of racial labels in biomedical research runs ...
Sickle cell disease (SCD), also simply called sickle cell, is a group of hemoglobin-related blood disorders that are typically inherited. [2] The most common type is known as sickle cell anemia. [2] Sickle cell anemia results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. [2]
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This would be similar to the hemoglobin allele which is responsible for sickle-cell disease, but solely in people with two copies; those with just one copy of the allele have a sickle cell trait and gain partial immunity to malaria as a result. This effect is called heterozygote advantage. [27]
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For instance, a varying English proficiency among immigrant Asian parents can be a source of conflict between parents and children. One study shows that in immigrant Chinese families, the level of English proficiency in the parental generation correlates with indicators of child and adolescent psychological well-being. [197]
He found that the prevalence of sickle-cell trait (heterozygous condition) among people inhabiting coastal areas was higher than 20%. [8] At the time the highest record was 8% among African-Americans.) [ 10 ] He was posed with the question as to why such a deadly disease (in homozygous condition ) would be more prevalent in a localised area in ...