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Vaping-associated pulmonary injury (VAPI), [4] also known as vaping-associated lung injury (VALI) [1] or e-cigarette, or vaping, product use associated lung injury (E/VALI), [2] [a] is an umbrella term, [15] [16] used to describe lung diseases associated with the use of vaping products that can be severe and life-threatening. [3]
[128] [75]: 12 A 2014 study reported that limited evidence suggests that e-cigarettes produce less short-term effects on lung function than traditional cigarettes. [129] As of 2015 many e-liquid ingredients had not been examined in the lung. [98] As of 2017 e-cigarette effects on asthma and other respiratory diseases had not been assessed. [11 ...
However, e-cigarette use with or without nicotine cannot be considered risk-free [163] because the long-term effects of e-cigarette use are unknown. [97] [149] [160] Possible side effects of nicotine [164] The cytotoxicity of e-liquids varies, [165] and contamination with various chemicals have been detected in the liquid. [34]
The common side effects from nicotine exposure are listed in the table below. Serious adverse events due to the use of nicotine replacement therapy are extremely rare. [ 47 ] At low amounts, it has a mild analgesic effect. [ 38 ]
Though smoking has declined significantly over the decades, nearly one in eight American adults still smoke, and cigarette smoking kills more than 480,000 Americans a year, government data show.
Frequently reported brand names of THC and nicotine-containing e-cigarette or vaping products reported by patients with lung injury — Illinois and Wisconsin, 2019 [69] Inhalation of chemicals or substances is considered to be the main cause of the lung illnesses. [70] Counterfeit cannabis cartridges are being sold to users at a reduced cost. [71]
The LD 50 of nicotine is 50 mg/kg for rats and 3 mg/kg for mice. 0.5–1.0 mg/kg can be a lethal dosage for adult humans, and 0.1 mg/kg for children. [19] [20] However the widely used human LD 50 estimate of 0.5–1.0 mg/kg was questioned in a 2013 review, in light of several documented cases of humans surviving much higher doses; the 2013 review suggests that the lower limit causing fatal ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 6 February 2025. Circumstances, mechanisms, and factors of tobacco consumption on human health "Health effects of smoking" and "Dangers of smoking" redirect here. For cannabis, see Effects of cannabis. For smoking crack cocaine, see Crack cocaine § Health issues. "Smoking and health" redirects here. For ...