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In humans there are two isoforms of PEPCK; a cytosolic form (SwissProt P35558) and a mitochondrial isoform (SwissProt Q16822) which have 63.4% sequence identity. The cytosolic form is important in gluconeogenesis.
Phosphoenolpyruvate carboxykinase 2, mitochondrial (PCK2, PEPCK-M), is an isozyme of phosphoenolpyruvate carboxykinase (PCK, PEPCK) that in humans is encoded by the PCK2 gene on chromosome 14. This gene encodes a mitochondrial enzyme that catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) in the presence of guanosine ...
Phosphoenolpyruvate carboxykinase (ATP) (EC 4.1.1.49, phosphopyruvate carboxylase (ATP), phosphoenolpyruvate carboxylase, phosphoenolpyruvate carboxykinase, phosphopyruvate carboxykinase (adenosine triphosphate), PEP carboxylase, PEP carboxykinase, PEPCK (ATP), PEPK, PEPCK, phosphoenolpyruvic carboxylase, phosphoenolpyruvic carboxykinase, phosphoenolpyruvate carboxylase (ATP), phosphopyruvate ...
18534 Ensembl ENSG00000124253 ENSMUSG00000027513 UniProt P35558 Q9Z2V4 RefSeq (mRNA) NM_002591 NM_011044 RefSeq (protein) NP_002582 NP_035174 Location (UCSC) Chr 20: 57.56 – 57.57 Mb Chr 2: 172.99 – 173 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Phosphoenolpyruvate carboxykinase 1 (soluble), also known as PCK1, is an enzyme which in humans is encoded by the PCK1 gene ...
The location of the enzyme that links these two parts of gluconeogenesis by converting oxaloacetate to PEP – PEP carboxykinase (PEPCK) – is variable by species: it can be found entirely within the mitochondria, entirely within the cytosol, or dispersed evenly between the two, as it is in humans. [27]
According to Iglesias, human development in fire-prone regions, especially in the wildland-urban interface, where neighborhoods mingle with forest and grasslands, has introduced new, highly ...
18563 Ensembl ENSG00000173599 ENSMUSG00000024892 UniProt P11498 Q05920 RefSeq (mRNA) NM_000920 NM_001040716 NM_022172 NM_001162946 NM_008797 RefSeq (protein) NP_000911 NP_001035806 NP_071504 n/a Location (UCSC) Chr 11: 66.85 – 66.96 Mb Chr 19: 4.56 – 4.67 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Pyruvate carboxylase (PC) encoded by the gene PC is an enzyme (EC 6.4.1.1) of ...
Russo died from cervical cancer at 37 years old in 2006, and her sister, Eileen Lind, founded a nonprofit, Team Maureen, to raise awareness on human papillomavirus (HPV) vaccination to reduce risk ...