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Bowel infarction or gangrenous bowel represents an irreversible injury to the intestine resulting from insufficient blood flow. It is considered a medical emergency because it can quickly result in life-threatening infection and death. [1] Any cause of bowel ischemia, the earlier reversible form of injury, may ultimately lead to infarction if ...
The treatment of intestinal ischemia depends on the cause and can be medical or surgical. However, if bowel has become necrotic, the only treatment is surgical removal of the dead segments of bowel. [34] In non-occlusive disease, where there is no blockage of the arteries supplying the bowel, the treatment is medical rather than surgical ...
Patients with pre-existing peripheral vascular disease or ischemia of the ascending (right) colon may be at increased risk for complications or death. [ citation needed ] Non-gangrenous ischemic colitis, which comprises the vast majority of cases, is associated with a mortality rate of approximately 6%. [ 34 ]
Volvulus causes severe pain and progressive injury to the intestinal wall, with accumulation of gas and fluid in the portion of the bowel obstructed. [11] Ultimately, this can result in necrosis of the affected intestinal wall, acidosis, and death. This is known as a closed-loop obstruction because there exists an isolated ("closed") loop of bowel.
Coagulative necrosis is a type of accidental cell death typically caused by ischemia or infarction. In coagulative necrosis, the architectures of dead tissue are preserved for at least a couple of days. [1] It is believed that the injury denatures structural proteins as well as lysosomal enzymes, thus blocking the proteolysis of the damaged cells.
Before her death, Maddie was an "extraordinary big sister” to her then-3-month-old sibling, too. Related: 5-Year-Old Dies After Being Misdiagnosed by Doctors Who Said She Had a Cold.
Ischemia is a vascular disease involving an interruption in the arterial blood supply to a tissue, organ, or extremity that, if untreated, can lead to tissue death. It can be caused by embolism , thrombosis of an atherosclerotic artery, or trauma.
Infarction is tissue death due to inadequate blood supply to the affected area. It may be caused by artery blockages , rupture, mechanical compression, or vasoconstriction . [ 1 ] The resulting lesion is referred to as an infarct [ 2 ] [ 3 ] (from the Latin infarctus , "stuffed into").