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In March 2017, ocrelizumab was approved in the United States for the treatment of primary progressive multiple sclerosis in adults. [22] [42] It is also used for the treatment of relapsing forms of multiple sclerosis, to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease in adults. [42]
Multiple sclerosis (MS) is an autoimmune disease resulting in damage to the insulating covers of nerve cells in the brain and spinal cord. [3] As a demyelinating disease , MS disrupts the nervous system's ability to transmit signals , resulting in a range of signs and symptoms , including physical, mental , and sometimes psychiatric problems.
Multiple sclerosis can be pathologically defined as the presence of distributed glial scars (or sclerosis) in the central nervous system disseminated in time (DIT) and space (DIS). [2] The gold standard for MS diagnosis is pathological correlation, though given its limited availability, other diagnosis methods are normally used. [ 3 ]
Multiple Sclerosis Discovery Forum (MSDF) is a non-profit online resource [1] created to speed progress toward a cure for multiple sclerosis (MS) and other demyelinating diseases by enabling faster sharing of information and free discussion among MS researchers in academia, industry, and the clinic.
The McDonald criteria are diagnostic criteria for multiple sclerosis (MS). These criteria are named after neurologist W. Ian McDonald who directed an international panel in association with the National Multiple Sclerosis Society (NMSS) of America and recommended revised diagnostic criteria for MS in April 2001.
The National Multiple Sclerosis Society (NMSS) was founded in New York City as the Association for Advancement of Research on Multiple Sclerosis on March 11, 1946 by Sylvia Lawry, [1] a lawyer seeking a cure for her brother, Bernard, who suffered from multiple sclerosis. Recognizing the absence of any existing foundation or organization aiding ...
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