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Gene duplication (or chromosomal duplication or gene amplification) is a major mechanism through which new genetic material is generated during molecular evolution. It can be defined as any duplication of a region of DNA that contains a gene .
Chữ khoa đẩu is a term claimed by the Vietnamese pseudohistorian Đỗ Văn Xuyền to be an ancient, pre-Sinitic script for the Vietnamese language. Đỗ Văn Xuyền's works supposedly shows the script have been in use during the Hồng Bàng period, and it is believed to have disappeared later during the Chinese domination of Vietnam .
Evolution by gene duplication is an event by which a gene or part of a gene can have two identical copies that can not be distinguished from each other. This phenomenon is understood to be an important source of novelty in evolution, providing for an expanded repertoire of molecular activities.
The 2R hypothesis saw a resurgence of interest in the 1990s for two reasons. First, gene mapping data in humans and mice revealed extensive paralogy regions - sets of genes on one chromosome related to sets of genes on another chromosome in the same species, indicative of duplication events in evolution. [9]
Misalignment of LCRs during non-allelic homologous recombination (NAHR) [3] is an important mechanism underlying the chromosomal microdeletion disorders as well as their reciprocal duplication partners. [4] Many LCRs are concentrated in "hotspots", such as the 17p11-12 region, 27% of which is composed of LCR sequence.
Single gene duplication is a random process and tends to make duplicated genes scattered throughout the genome. Duplicated blocks are non-overlapping because they were created simultaneously. Segmental duplication within the genome can fulfill the first rule; but multiple independent segmental duplications could overlap each other. [18]
Gene duplication, a process which can result in free mutation; Chromosomal duplication, which can cause Bloom and Rett syndrome; Polyploidy, a phenomenon also known as ancient genome duplication; Enteric duplication cysts, certain portions of the gastrointestinal tract; Diprosopus, a form of cojoined twins also known as craniofacial duplication
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