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In chemistry, aminolysis (/am·i·nol·y·sis/) is any chemical reaction in which a molecule is lysed (split into two parts) by reacting with ammonia (NH 3) or an amine. [1] The case where the reaction involves ammonia may be more specifically referred to as ammonolysis .
In chemistry, ammonolysis (/am·mo·nol·y·sis/) is the process of splitting ammonia into + +. [1] Ammonolysis reactions can be conducted with organic compounds to produce amines (molecules containing a nitrogen atom with a lone pair, :N), [2] or with inorganic compounds to produce nitrides.
The activated intermediate species attacked by the amine during aminolysis is the HOBt ester. To create the HOBt ester, the carboxyl group of the acid attacks the imide carbonyl carbon of HBTU. Subsequently, the displaced anionic benzotriazole N-oxide attacks of the acid carbonyl, giving the tetramethyl urea byproduct and the activated ester.
General chemical structure of an acyl chloride. In organic chemistry, an acyl chloride (or acid chloride) is an organic compound with the functional group −C(=O)Cl.Their formula is usually written R−COCl, where R is a side chain.
2-Pyridone catalyses a variety of proton-dependent reactions, for example the aminolysis of esters. In some cases, molten 2-pyridone is used as a solvent. 2-Pyridone has a large effect on the reaction from activated esters with amines in nonpolar solvent, which is attributed to its tautomerisation and utility as a ditopic receptor.
Well-known types of reactions that involve inorganic compounds include: . Alkylation; Alkyne trimerisation; Alkyne metathesis; Aminolysis; Amination; Arylation; Barbier reaction; Beta-hydride elimination
For certain nucleophiles, solvolysis reactions are classified. Solvolysis involving water is called hydrolysis.Related terms are alcoholysis and specifically methanolysis (), acetolysis, ammonolysis (), and aminolysis (alkyl amines).
The Zincke reaction is an organic reaction, named after Theodor Zincke, in which a pyridine is transformed into a pyridinium salt by reaction with 2,4-dinitro-chlorobenzene and a primary amine.