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Diphenhydramine is the primary constituent of dimenhydrinate and dictates the primary effect. The main differences relative to pure diphenhydramine are a lower potency due to being combined with 8-chlorotheophylline (by weight, dimenhydrinate is between 53% and 55.5% diphenhydramine) [10] and the fact that the stimulant properties of 8-chlorotheophylline help reduce the side ...
Hydroxyzine, sold under the brand names Atarax and Vistaril among others, is an antihistamine medication. [8] It is used in the treatment of itchiness, anxiety, insomnia, and nausea (including that due to motion sickness). [8]
"Treatment of vertigo due to acute unilateral vestibular loss with a fixed combination of cinnarizine and dimenhydrinate: a double-blind, randomized, parallel-group clinical study". Clin Ther . 26 (6): 866– 77.
The drug has formed a salt with Cl- ions so that is nonreactive in the pill form and can be stored easily, once it enters the low pH of the stomach the Cl dissociates (comes off) and the drug can begin its metabolic activity, e.g. the effects discussed.98.240.251.209 05:51, 15 November 2008 (UTC)
Diphenhydramine, sold under the brand name Benadryl among others, is an antihistamine and sedative.It is a first-generation H 1-antihistamine and it works by blocking certain effects of histamine, which produces its antihistamine and sedative effects.
Orphenadrine (sold under many brand names) [1] is an anticholinergic drug of the ethanolamine antihistamine class; it is closely related to diphenhydramine.It is a muscle relaxant that is used to treat muscle pain and to help with motor control in Parkinson's disease, but has largely been superseded by newer drugs.
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