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Human genetic variants that likely cause dysregulation of critical meiotic processes have been identified in 14 female infertility associated genes. [53] A major cause of female infertility is premature ovarian insufficiency. [54] This insufficiency is a heterogeneous disease that affects about 1% of women who are under the age of 40. [54]
Female fertility agents are medications that improve female’s ability to conceive pregnancy. These agents are prescribed for infertile female who fails to conceive pregnancy after 1-year of regular and unprotected sexual intercourse. [1] The following will cover the advancements of female fertility agents, major causes of female infertility.
The postcoital test (PCT), also known as the Sims test, Hühner test ,Sims–Hühner test, or cervical mucous penetration assay is a test in the evaluation of infertility. The test examines interaction between sperm and mucus of the cervix .
Male infertility is responsible for 20–30% of infertility cases, while 20–35% are due to female infertility, and 25–40% are due to combined problems in both partners. [29] [5] In 10–20% of cases, no cause is found. [5] The most common cause of female infertility are ovulation problems, usually manifested by scanty or absent menstrual ...
The investigators measured the relationship between the age of the female partner and fertility. (Infertility rates today are believed to be higher in the general population than for the population in this study from the 1950s.) This 1957 study found that: [22] By age 30, 7% of couples were infertile; By age 35, 11% of couples were infertile
Chronic anovulation is a common cause of infertility. In addition to the alteration of menstrual periods and infertility, chronic anovulation can cause or exacerbate other long-term problems, such as hyperandrogenism or osteopenia. It plays a central role in the multiple imbalances and dysfunctions of polycystic ovary syndrome.
The Rubin test became a standard test to check the tubes in the investigation of causes of infertility and was claimed to be able to open up tubes in some patients with tubal occlusion. [5] In 1958, Speert stated that "many gynecologists regard it as the twentieth century's most important contribution to the clinical study of female infertility."
In the United States, fellowship in reproductive endocrinology and infertility usually takes 3 years, and is offered in 40 centers across the country as of 2013. [ 2 ] In the European Union , the European Board and College of Obstetrics and Gynaecology (EBCOG) has accreditation centers for a subspecialist training program in reproductive ...
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