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  2. Hypodermic needle - Wikipedia

    en.wikipedia.org/wiki/Hypodermic_needle

    It is estimated that anywhere from nearly 3.5 to 10% of the world's population may have a phobia of needles (trypanophobia), [25] and it is much more common in children, ages 5–17. Topical anesthetics can be used to desensitize the area where the injection will take place to reduce pain and discomfort. [ 26 ]

  3. Injector pen - Wikipedia

    en.wikipedia.org/wiki/Injector_pen

    Many insulin analogs and GLP-1 agonists for diabetes treatment are available as injector pens. [2] As with insulin vials, some insulin pens are made with higher concentrations including U-200, U-300, and U-500. Different concentration insulin products may not have the same pharmacokinetic properties as other strengths. [10]

  4. Syringe - Wikipedia

    en.wikipedia.org/wiki/Syringe

    The dilution of insulin is such that 1 mL of insulin fluid has 100 standard "units" of insulin. [6] A typical insulin vial may contain 10 mL, for 1000 units. Insulin syringes are made specifically for a patient to inject themselves, and have features to assist this purpose when compared to a syringe for use by a healthcare professional:

  5. Insulin (medication) - Wikipedia

    en.wikipedia.org/wiki/Insulin_(medication)

    The combination products begin to work with the shorter-acting insulin (5–15 minutes for fast-acting, and 30 minutes for short-acting), and remain active for 16–24 hours. There are several variations with different proportions of the mixed insulins (e.g. Novolog Mix 70/30 contains 70% aspart protamine [akin to NPH], and 30% aspart.) [49]

  6. Eli Lilly and Company - Wikipedia

    en.wikipedia.org/wiki/Eli_Lilly_and_Company

    The annual cost of insulin for people with type 1 diabetes in the US almost doubled from $2,900 to $5,700 over the period from 2012 to 2016. [269] Renewed attention was brought to Eli Lilly's pricing of insulin in November 2022, after a verified Twitter account impersonating Eli Lilly posted on Twitter that insulin would now be free.

  7. Insulin glargine - Wikipedia

    en.wikipedia.org/wiki/Insulin_glargine

    Insulin glargine differs from human insulin by replacing asparagine with glycine in position 21 of the A-chain and by carboxy-terminal extension of B-chain by 2 arginine residues. The arginine amino acids shift the isoelectric point from a pH of 5.4 to 6.7, making the molecule more soluble at an acidic pH and less soluble at physiological pH.

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