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Adenocarcinoma in situ (AIS) of the lung —previously included in the category of "bronchioloalveolar carcinoma" (BAC)—is a subtype of lung adenocarcinoma.It tends to arise in the distal bronchioles or alveoli and is defined by a non-invasive growth pattern.
Carcinoma in situ (CIS) is a group of abnormal cells. [ 1 ] [ 2 ] While they are a form of neoplasm , [ 3 ] there is disagreement over whether CIS should be classified as cancer . This controversy also depends on the exact CIS in question (e.g., cervical, skin, breast).
A drawing of ductal carcinoma in situ in the anatomical context of the whole breast A drawing of a breast duct containing ductal carcinoma in situ. Most of the women who develop DCIS do not experience any symptoms. The majority of cases (80-85%) are detected through screening mammography. The first signs and symptoms may appear if the cancer ...
The approach is similar to that of late "Grease" star Olivia Newton-John, from whom Macpherson sought advice after the actor famously complemented her clinical treatment for breast cancer with ...
Lobular carcinoma in situ is both a risk factor and precursor of invasive carcinoma. Furthermore, it is a non-obligate precursor. In other words, LCIS represents a distinct entity in the developmental pathway of cancer that does not guarantee invasive carcinoma.
PDCIS is managed primarily by surgical removal in the same manner as ductal carcinoma in situ tumors that have the same nuclear grade and estrogen receptor expression by their tumor cells (see treatment of ductal carcinoma in situ). [3] (Nuclear grade describes how closely the nuclei of cancer cells look like the nuclei of normal breast cells ...