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"Intravitreal" literally means "inside an eye". Intravitreal injections were first introduced in 1911 when Ohm gave an injection of air into the vitreous humor to repair a detached retina. In the mid-1940s, intravitreal injections became a standard way to administer drugs to treat endophthalmitis and cytomegalovirus retinitis. [1]
Intravitreal injection is the method of administration of drugs into the eye by injection with a fine needle. The medication will be directly applied into the vitreous humor . [ 1 ] It is used to treat various eye diseases, such as age-related macular degeneration (AMD) , diabetic retinopathy , and infections inside the eye such as ...
Vitreous hemorrhage is the extravasation, or leakage, of blood into the areas in and around the vitreous humor of the eye. [1] The vitreous humor is the clear gel ...
Intravitreal injection of Dexamethasone implant (Ozurdex; 700,350 μg) is being studied, its effect may last for 180 days. The injection may be repeated however with less pronounced effect. Although the implant was designed to cause less complications, pressure rise and cataract formation is noted with this treatment too. [6]
Intraocular hemorrhage (sometimes called hemophthalmos or hemophthalmia) is bleeding inside the eye (oculus in Latin).Bleeding can occur from any structure of the eye where there is vasculature or blood flow, including the anterior chamber, vitreous cavity, retina, choroid, suprachoroidal space, or optic disc.
Bevacizumab is an anti-VEGF drug used in intravitreal injection that is known to cause reversal of sea fan lesions and reduce the duration of vitreous hemorrhage. [ 3 ] [ 4 ] Intravitreal injection of anti-VEGF drugs can also be used prior to surgery to aid separation of tissues involved in the sea fan lesion and to reduce intraoperative and ...
The extent and location of the intraocular hemorrhage determine the degree of vision impairment. Because of clots or debris in the vitreous cavity, patients may suffer floaters, which are spots or threads in their field of vision. In extreme situations, extensive vitreous bleeding may result in a total loss of the red reflex.
A woman in Germany was sentenced to life in prison for murdering her "doppelgänger" in 2022. The victim's family in Algeria found out about the verdict three weeks later. They say they were kept ...