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Pharmaceutical company AstraZeneca said Enhertu demonstrated a 72% reduction in the risk of disease progression or death in women with HER2-positive metastatic breast cancer compared to a ...
Trastuzumab deruxtecan, sold under the brand name Enhertu, is an antibody-drug conjugate consisting of the humanized monoclonal antibody trastuzumab (Herceptin) covalently linked to the topoisomerase I inhibitor deruxtecan (a derivative of exatecan). [11] [12] It is licensed for the treatment of breast cancer or gastric or gastroesophageal ...
If approved for HER2 low and ultra-low breast cancers after endocrine therapy, eight out of out 10 women with metastatic breast cancer could be treated with Enhertu, AstraZeneca oncology research ...
The absolute reduction in the risk of cancer returning within three years was 9.5%, and the absolute reduction in the risk of death within 3 years was reduced by 3%. However, it increases serious heart problems by an absolute risk of 2.1%, though the problems may resolve if treatment is stopped.
Breast cancer incidence by age in women (UK) 2006-08 [21] Breast cancer is the most common cancer in the UK (around 56,000 women and 375 men are diagnosed with the disease every year). It is the fourth most common cause of cancer death (around 11,400 women and 85 men die each year) and the second most common cause of death in women. [22]
Meanwhile, the cancer death rate is declining, the new findings show, falling by a third from 1991 to 2021. That translates to 4.1 million lives saved. ... Those cancers include colorectal and ...
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