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A cluster-randomised controlled trial is a type of randomised controlled trial in which groups of subjects (as opposed to individual subjects) are randomised. [1] Cluster randomised controlled trials are also known as cluster-randomised trials, [2] group-randomised trials, [3] [4] and place-randomized trials. [5]
[1] [2] The crossover is in one direction, typically from control to intervention, with the intervention not removed once implemented. The stepped-wedge design can be used for individually randomized trials, [3] [4] i.e., trials where each individual is treated sequentially, but is more commonly used as a cluster randomized trial (CRT). [5]
Pipeline planning is a social audit that incorporates stepped wedge cluster randomised controlled trials. [1] From a listing of districts/communities as a sampling frame, individual entities (communities, towns, districts) are randomly assigned to waves of intervention.
A randomized controlled trial (or randomized control trial; [2] RCT) is a form of scientific experiment used to control factors not under direct experimental control. Examples of RCTs are clinical trials that compare the effects of drugs, surgical techniques, medical devices , diagnostic procedures , diets or other medical treatments.
Clinical trials units (CTU) are specialised biomedical research units which design, centrally coordinate and analyse clinical trials and other studies. Some CTUs specialise in different methodologies, such as randomised controlled trials , cluster randomised trials , surgical trials, and health services research.
Clinical trial portal; Clinical trial registration; Clinical trials publication; Clinical trials unit; Cluster-randomised controlled trial; Code-break procedure; Cohen's h; Common Technical Document; Common Terminology Criteria for Adverse Events; Community advisory board; Community-based clinical trial; Consecutive case series; Consecutive ...
A look at where the various court cases against President-elect Donald Trump stand, and how they may — or may not — be affected by his taking the oath of office on Jan. 20.
The main CONSORT Statement is based on the "standard" two-group parallel design. Extensions of the CONSORT Statement have been developed to give additional guidance for randomized trials with specific designs (e.g., cluster randomized trials, [3] noninferiority and equivalence trials, [4] pragmatic trials [5]), data (e.g., harms, [6] abstracts [7]), type of target outcome, [8] and various ...