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  2. Sonoporation - Wikipedia

    en.wikipedia.org/wiki/Sonoporation

    This technique is usually used in molecular biology and non-viral gene therapy in order to allow uptake of large molecules such as DNA into the cell, in a cell disruption process called transfection or transformation. Sonoporation employs the acoustic cavitation of microbubbles to enhance delivery of these large molecules. [1]

  3. Targeted therapy - Wikipedia

    en.wikipedia.org/wiki/Targeted_therapy

    Targeted Therapy Database (TTD) from the Melanoma Molecular Map Project Targeted therapy Fact sheet from the U.S. National Cancer Institute Molecular Oncology: Receptor-Based Therapy Special issue of Journal of Clinical Oncology (April 10, 2005) dedicated to targeted therapies in cancer treatment

  4. Antisense therapy - Wikipedia

    en.wikipedia.org/wiki/Antisense_therapy

    Antisense therapy is a form of treatment that uses antisense oligonucleotides (ASOs) to target messenger RNA (mRNA). ASOs are capable of altering mRNA expression through a variety of mechanisms, including ribonuclease H mediated decay of the pre-mRNA, direct steric blockage, and exon content modulation through splicing site binding on pre-mRNA ...

  5. Molecular biology - Wikipedia

    en.wikipedia.org/wiki/Molecular_biology

    Molecular biology is the study of the molecular underpinnings of the biological phenomena, focusing on molecular synthesis, modification, mechanisms and interactions. Biochemistry is the study of the chemical substances and vital processes occurring in living organisms .

  6. Gene therapy - Wikipedia

    en.wikipedia.org/wiki/Gene_therapy

    Gene therapy may be classified into two types by the type of cell it affects: somatic cell and germline gene therapy. In somatic cell gene therapy (SCGT), the therapeutic genes are transferred into any cell other than a gamete , germ cell , gametocyte , or undifferentiated stem cell .

  7. Molecular medicine - Wikipedia

    en.wikipedia.org/wiki/Molecular_medicine

    Molecular medicine is a broad field, where physical, chemical, biological, bioinformatics and medical techniques are used to describe molecular structures and mechanisms, identify fundamental molecular and genetic errors of disease, and to develop molecular interventions to correct them. [1]

  8. Biomedicine - Wikipedia

    en.wikipedia.org/wiki/Biomedicine

    Biomedicine involves the study of (patho-) physiological processes with methods from biology and physiology. Approaches range from understanding molecular interactions to the study of the consequences at the in vivo level. These processes are studied with the particular point of view of devising new strategies for diagnosis and therapy. [13] [14]

  9. RNA therapeutics - Wikipedia

    en.wikipedia.org/wiki/RNA_Therapeutics

    An example of one mimic miRNA therapy that demonstrated efficacy in impeding lung cancer tumor growth in mouse studies is miR-34a. [ 83 ] [ 84 ] One concerning aspect of miRNA-based therapies is the potential for the exogeneous miRNA to affect miRNA silencing mechanisms within normal body cells, thereby affecting normal cellular biochemical ...