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Ovarian hyperstimulation syndrome is particularly associated with injection of a hormone called human chorionic gonadotropin (hCG) which is used for inducing final oocyte maturation and/or triggering oocyte release. The risk is further increased by multiple doses of hCG after ovulation and if the procedure results in pregnancy. [2]
Human chorionic gonadotropin is a glycoprotein composed of 237 amino acids with a molecular mass of 36.7 kDa, approximately 14.5kDa αhCG and 22.2kDa βhCG. [4]It is heterodimeric, with an α (alpha) subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and a β (beta) subunit that is unique to hCG.
Using low dose human chorionic gonadotropin (hCG) to replace FSH during the late follicular phase in women undergoing hyperstimulation as part of IVF may make little or no difference to pregnancy rates, and possibly leads to in an equivalent number of oocytes retrieved, but with less expenditure of FSH. [22]
Human chorionic gonadotropin (HCG or hCG) in a low dose, which may be injected after completed ovarian stimulation. Final maturation with hCG is also termed hCG priming. [7] Ovulation will occur between 38 and 40 hours after a single HCG injection. [8] It is also used in in vitro fertilization, where it makes the follicles perform their final ...
Human chorionic gonadotropin (hCG), also known as the “hormone of pregnancy” is a hormone that is normally produced during pregnancy and plays an integral role throughout reproduction. [16] It is crucial in maintaining pregnancy, from the stages of placentation to early embryo development. [16]
menotropins for injections, USP. Brands. Menopur, 5 mL vials containing 75 IU FSH and 75 IU LH. Repronex, vials containing either 75 IU FSH and 75 IU LH, or 150 IU FSH and 150 IU LH. Common side effects of preparations containing FSH and LH are: [4] Mild bloating; Pain, swelling, or irritation injection site; Rash at injection site or other ...
Gonadotropin therapy refers to the administration of exogenous gonadotropins to treat anovulation. [6] Gonadotropin therapy is given via intrauterine insemination (IUI) and in vitro fertilization (IVF) to exert its effects. [7] FSH promotes the recruitment and maturation of early antral follicles, while LH helps follicular development and ...
As a result of the 1992 Fertility Clinic Success Rate and Certification Act, the CDC is required to publish the annual ART success rates at U.S. fertility clinics. [29] Assisted reproductive technology procedures performed in the U.S. has over than doubled over the last 10 years, with 140,000 procedures in 2006, [ 30 ] resulting in 55,000 births.