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"Moon blindness" on an Icelandic horse Advanced stage of disease Advanced stage of disease ERU on an Icelandic horse. Equine recurrent uveitis (ERU) – also known as moon blindness, recurrent iridocyclitis, or periodic ophthalmia [1] – is an acute, nongranulomatous inflammation of the uveal tract of the eye, occurring commonly in horses of all breeds, worldwide.
Visual perception in animals plays an important role in the animal kingdom, most importantly for the identification of food sources and avoidance of predators. For this reason, blindness in animals is a unique topic of study. In general, nocturnal or subterranean animals have less interest in the visual world, and depend on other sensory ...
The part of the retina covered by light-sensitive cells is therefore termed the pars-optica retinae, and the blind part of the eye is termed the pars-ceaca retinae. The optic disk of the eye, however, does not contain any of these light-sensitive cells, as it is where the optic nerve leaves to the brain, so is a blind spot within the eye. [3]
The disease may progress to severe inflammation of the uveal layer of the eye (uveitis) with pain and sensitivity of the eyes to light. The affected eye often remains relatively painless while the inflammatory disease spreads through the uvea , where characteristic focal infiltrates in the choroid named Dalén–Fuchs nodules can be seen.
Uveitis is estimated to be responsible for approximately 10%-20% of the blindness in the United States. [ 36 ] For non-infectious uveitis, women are more likely (57%) to be affected than men, possibly due to their higher prevalence of related autoimmune diseases . [ 37 ]
Because uveitic glaucoma is a progressive stage of anterior non infectious uveitis, uveitic glaucoma involves signs and symptoms of both glaucoma and uveitis.. Patients with acute non infectious anterior uveitis may experience the following symptoms: pain, blurry vision, headache, photophobia (discomfort or pain due to light exposure), or the observance of haloes around lights.
People taking Ozempic and Wegovy may be at increased risk of developing a debilitating eye condition that can cause irreversible vision loss, a study published in JAMA Ophthalmology finds.
KCS is a chronic degenerative conjunctivitis that can lead to impaired vision and blindness. [2] KCS has a wide array of causes including drug toxicity, cherry eye, previous surgery, trauma, and irradiation. [2] KCS can be treated, but treatment often spans the entirety of the animal's life. [2]