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A retroverted uterus (tilted uterus, tipped uterus) is a uterus that is oriented posteriorly, towards the rectum in the back of the body. This is in contrast to the typical uterus, which is oriented forward (slightly " anteverted ") toward the bladder , with the anterior part slightly concave.
Complete androgen insensitivity syndrome (CAIS) is an AIS condition that results in the complete inability of the cell to respond to androgens. [1] [2] [3] As such, the insensitivity to androgens is only clinically significant when it occurs in individuals who are exposed to significant amounts of testosterone at some point in their lives. [1]
A retroverted, or "tilted," uterus won't affect your fertility or pregnancy. However, it can cause pain during menstruation, sex, and recurrent UTIs.
Transgender men who have any bleeding after the cessation of menses with androgen therapy should be evaluated for age appropriate causes of abnormal uterine bleeding as per cisgender female guidelines. [38] Adults with a uterus/cervix are advised to have a Pap smear per guidelines (Human papillomavirus infection). Use of testosterone is no ...
Thus, the presence of an early pregnancy in a retroverted uterus is not considered a problem. [1] On rare occasions the uterus fails to become anteverted, and the pregnancy continues to expand the retroverted uterus within the confines of the pelvis. By about 14 weeks the size of the uterus fills out most of the pelvis, pushing up the cervix.
Sertoli cells within the testes secrete anti-Müllerian hormone around this time to suppress the development of the Müllerian ducts, and cause their degeneration. [67] Without this anti-Müllerian hormone, the Müllerian ducts develop into the female internal genitalia (uterus, cervix, fallopian tubes, and upper vaginal barrel). [67]