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Dutasteride is sometimes used as a component of hormone therapy for transgender women in combination with an estrogen and/or another antiandrogen such as spironolactone. [7] It may be useful for preventing and treating scalp hair loss and can also be used as a general antiandrogen for in those who have issues tolerating spironolactone, though as a α-reductase inhibitor it has limited effects ...
Dutasteride (brand name Avodart) inhibits all three 5α-reductase isoenzymes and can decrease DHT levels by 95%. [9] [10] It can also reduce DHT levels in the prostate by 97 to 99% in men with prostate cancer. [11] [12] Epristeride (brand names Aipuliete, Chuanliu) is marketed in China for the treatment of benign prostatic hyperplasia.
Three medications have evidence to support their use in male pattern hair loss: finasteride, dutasteride and minoxidil. [15] They typically work better to prevent further hair loss than to regrow lost hair. [15] They may be used together when hair loss is progressive or further regrowth is desired after 12 months. [16]
Dutasteride (Avodart) was the second steroidal 5α-reductase approved after finasteride. It is a competitive inhibitor of all three 5α-reductase isoenzymes [ 4 ] and it inhibits types 1 and 2 better than finasteride, leading to it causing further reduction in DHT, with >90% reduced DHT levels following 1 year of oral administration.
They are powerful antigonadotropins and work by abolishing the GnRH-induced secretion of gonadotropins, in turn ceasing gonadal production of sex hormones. [31] Medical and surgical castration achieve essentially the same effect, decreasing circulating testosterone levels by approximately 95%.
Instead of giving cash, you can donate appreciated stocks, avoid capital gains taxes and still claim a tax deduction for the full value of the donation. Plus, charities can sell the stock tax-free ...
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The American Cancer Society, a non-profit organization dedicated to eliminating the disease, called on the administration to "restore access to comprehensive data, refrain from changes that would ...
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