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The strain of Yersinia pestis responsible for the Black Death, the devastating pandemic of bubonic plague, does not appear to be a direct descendant of the Justinian plague strain. However, the spread of Justinian plague may have caused the evolutionary radiation that gave rise to the currently extant 0ANT.1 clade of strains. [44] [45]
Plague of Justinian: Bubonic plague 15–100 million 25–60% of European population [5] 541–549 North Africa, Europe, and Western Asia 3 HIV/AIDS pandemic: HIV/AIDS: 44 million (as of 2025) [a] 1981–present [6] Worldwide 1 Black Death: Bubonic plague: 75-200 Miliion 30–60% of European population [7] 1346–1353 Europe, Asia, and North ...
An outbreak in 1471 took as much as 10–15% of the population, while the death rate of the plague of 1479–80 could have been as high as 20%. [35] The most general outbreaks in Tudor and Stuart England seem to have begun in 1498, 1535, 1543, 1563, 1589, 1603, 1625, and 1636, and ended with the Great Plague of London in 1665. [36]
The Black Death in the 14th century was perhaps the most infamous plague epidemic, killing up to half of the population as it spread through Europe, the Middle East and northern Africa. It began ...
The first plague pandemic was the first historically recorded Old World pandemic of plague, the contagious disease caused by the bacterium Yersinia pestis. Also called the early medieval pandemic, it began with the Plague of Justinian in 541 and continued until 750 or 767. At least fifteen to eighteen major waves of plague following the ...
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A book written by David Keys speculates that the climate changes contributed to various developments, such as the emergence of the Plague of Justinian (541–549), the decline of the Avars, the migration of Mongol tribes towards the west, the end of the Sasanian Empire, the collapse of the Gupta Empire, the rise of Islam, the expansion of ...
Today COVID-19 is terrible, but compare the death rate for bubonic plague." He pointed to the 1.8% case-fatality ratio in the United States compared to the 40% to 60% mortality rate for untreated ...